Squalene – Repair Damaged Cells, Anti-tumor

Extracted from deep ocean fish, Squalene can activate cells and increase oxygen intake, repair damaged cells, increase metabolism and blood ciculation, strengthen the body’s immune system, remove toxins from the body, regulate pain and restore physical health.


Squalene is one of the top ingredients included in Stem Cell in Capsule.


Squalene oil is found in abundance within shark liver oil, it’s also found in high amounts in olive oil, and can be produced by plants and humans.

There are a huge number of must-have natural supplements available in the market today.

Equally, there are a number of reasons why squalene is touted as one of the best anti-aging supplements around, including;

• Helps to boost your immune system
• Help support against joint pain and conditions like arthritis
• Rejuvenating dry and dull hair, skin and nails
• Supporting a healthy skin complexion
• Reducing the signs of aging

As it turns out, it’s packed with many nourishing compounds and has been a part of the traditional diets of many cultures around the world for centuries.

It’s a substance that is found in varying concentrations in almost all plants and animals (including humans!).

Newborn babies have the highest levels of squalene in their body, with natural production decreasing as we enter middle age.

It’s needed for the body to synthesize (create) hormones, cholesterol, and vitamin D, and also plays a role in many other functions of the body.

SOURCE: https://www.nzhealthfood.com/blog/squalene-shark-liver-oil-benefits/


Biological activities of squalene

Squalene appears to be critical for reducing free radical oxidative damage to the skin. Serum squalene originates partly from endogenous cholesterol synthesis and partly from dietary sources, especially in populations consuming large amounts of olive oil or shark liver []. The endogenous synthesis of squalene begins with the production of 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA). The initial reduction of HMG CoA (a niacin-dependent reaction) results in the formation of mevalonate [].

Sebaceous glands are small glands in the skin which secrete an oily matter (sebum) in the hair follicles to lubricate the skin and hair of animals (Figure 2). In humans, they are found in the greatest abundance on the face and scalp, although they are distributed throughout all skin sites except the palms and soles. Squalene is one of the predominant components (about 13%) of sebum (Table 1) [].

SOURCE: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6253993/

Antitumor activities

During the past few years, squalene was found to show protective activities against several carcinogens []. Desai et al. [] reported that skin tumors were initiated in 50 female CD-l mice with 7,12-dimethylbenz[a]anthracene and promoted with 12-O-tetradecanoylphorbol-13-acetate. The mice were treated with 5% squalene and at the end of the prevention study, there was a 26.67% reduction in the incidence of tumors in the squalene-treated group. In a related branch of research, a protective effect was observed when squalene was given before and/or during carcinogen treatment. Experimental studies have shown that squalene can effectively inhibit chemically induced skin tumorigenesis in rodents [].

SOURCE: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6253993/

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